Graded against 178,763 supplements and 757 reviewed supplement and medication pairs, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Boron
MineralLast updated April 2026
AVELOR SUMMARY
Boron is an ultra-trace mineral with emerging evidence for bone health, testosterone support, and cognitive function. Our research shows it influences calcium, magnesium, and vitamin D metabolism, and may modestly increase free testosterone by reducing SHBG, but the evidence base is thin and mostly observational. It's cheap, safe at low doses, and likely beneficial for people with inadequate dietary intake.
EVIDENCE GRADES
Bone mineral density (postmenopausal women)observational + interventional
Moderate evidenceGrade B-
Testosterone (free testosterone via SHBG reduction)small studies (PMID: 21129941)
Limited evidenceGrade C+
Cognitive function
Limited evidenceGrade C
Arthritis / joint health
Limited evidenceGrade C
Vitamin D metabolismMay increase 25(OH)D levels when boron-depleted
Limited evidenceGrade C+
WHAT IT DOES
Boron influences the metabolism of calcium, magnesium, phosphorus, and vitamin D. It inhibits the hydroxylase enzymes that deactivate 17β-estradiol and vitamin D, effectively extending their half-lives. Boron also reduces SHBG (sex hormone-binding globulin), which increases free testosterone, though the magnitude is modest.
Dietary boron comes from fruits, vegetables, nuts, and legumes. Average dietary intake is 1-3mg/day. The proposed adequate intake is 1-13mg/day depending on the source.
OPTIMAL DOSAGE
General support: 3-6mg/day
Bone health: 3-6mg/day (combined with calcium, D, and magnesium)
Independently graded against 178,763 indexed supplements and 757 reviewed supplement and medication pairs, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated: April 2026
Not medical advice. Based on published clinical research and systematic reviews.