Phase-matched nutrients for hormonal balance
Unlock the full 28-Day Cycle-Sync Protocol with exact doses, brand recommendations, and interaction checks.
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Magnesium supplementation improved PMS symptoms in an open-label study without a control group (Quaranta et al., 2007, PMID 17177579); the authors describe it as preliminary. Calcium at 1200mg/day reduces PMS severity by 48% (Thys-Jacobs et al., 1998). DIM shifted the ratio of 2-hydroxyestrone to 16-alpha-hydroxyestrone in a phase I pilot (Rajoria et al., 2011, PMID 21254914). Those patients had thyroid proliferative disease, not a healthy cycling population. Chasteberry (Vitex agnus-castus) reduces PMS symptoms by modulating prolactin and supporting progesterone (Schellenberg et al., 2001).
Iron and magnesium helped replenish what was lost during menstruation. Omega-3s reduced prostaglandin-driven cramps. As energy returns, your body is ready for the follicular phase surge.
B vitamins supported rising estrogen metabolism. Probiotics ensured proper estrogen clearance through the gut. Zinc supported follicle development. Energy should be noticeably higher.
DIM and Calcium D-Glucarate are supporting liver clearance of peak estrogen levels. NAC provides additional detox support. This is your highest energy phase. Vitamin C primes progesterone production.
Magnesium, B6, and calcium worked together to reduce PMS symptoms. Chasteberry supported progesterone balance. Saffron improved luteal mood. This protocol repeats automatically with each cycle.
These protocols are based on published peer-reviewed research and are not medical advice. Consult your healthcare provider before starting any supplement regimen, especially if you take prescription medications.